Here is some additional information that will help you understand how Profile-NEST works:
•Profile-NEST allows you to nest 2 Axis Profiling toolpath operations onto one or more nested sheets. You can have multiple nest setups within the same Machining Job. Each are listed in the order they are processed in the Machining Job.
•The Machining Job can have one or more Setups called 
Operations to Nest. If you expand a Setup in the Machining Job you will see that it has a set of Nesting Parameters assigned to it. You can adjust these parameters individually for each Setup. When you Regenerate a Setup the toolpath operations contained within it are updated and its associated nested sheets are also updated. Regenerating a toolpath operation will also update its associated nested sheets.
•When Nested Sheets are generated they are listed under the Setup they are associated with.